Bilirubin direkt
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Bilirubin - Direkt - Laboreredmények - WEBBeteg. Bilirubin - Direkt normálérték: < 5 Bővebben Az én laboreredményem: Alacsonyabb Normál Magasabb Kérjük, válassza ki, hogy a laborlelete alapján az Ön Bilirubin - Direkt szintje alacsonyabb vagy magasabb-e a normálértéknél. Ha magasabb.. Direkt-bilirubin | Házipatika. A direkt bilirubin a vérfesték egyik lebontási terméke, szintje májzsugor, májgyulladás, zsírmáj, májdaganat, illetve epeút-elzáródás, epekő, hasnyálmirigy-betegségek esetén emelkedhet. Kategória Vérvizsgálat Típus Vérszérumból készült klinikai kémia. Normál érték 7 mmol/l (4 mg/l) alatt Mit mér a vizsgálat?. Magas bilirubin: direkt, indirekt és összbilirubin értékek . - Medy. Magas direkt (konjugált) bilirubin érték lehetséges okai Amennyiben az emelkedett totál bilirubinszintet elsősorban a direkt forma felszaporodása okozza (konjugált hiperbilirubinémia), a háttérben gyakran valamilyen epeelfolyási akadály vagy májbetegség áll.. Bilirubin direkt - Medicover. Bilirubin direkt. A bilirubin elnevezése a latin bilis (epe) és ruber (vörös) szavakból származik. Azokban a szervekben termelődik, amelyek részt vesznek a vörösvértestek lebontásában - a lépben, májban és egyes nyirokcsomókban. Más néven epefesték, és a hemoglobin lebontási terméke, mely sárga színű. Élettartama .. Mit jelent a bilirubin a laborleletben? | Dr. Girhiny Tamás. A bilirubin szerkezete folyamatosan módosul, a vérből egyrészt ezen formák összességét nézzük Totál, azaz teljes megnevezéssel, másrészt a direkt formát. Normál körülmények értéke között: felnőttekben a totál bilirubin < 20 umol/L, direkt formája pedig < 5,1 umol/l újszülöttekben 320 < umol/l Milyen esetekben magas a bilirubin?. Bilirubin direkt - Magánkórház és Magánklinika - Medicover Kórház. Bilirubin direkt A bilirubin elnevezése a latin bilis (epe) és ruber (vörös) szavakból származik. Azokban a szervekben termelődik, amelyek részt vesznek a vörösvértestek lebontásában - a lépben, májban és egyes nyirokcsomókban.. Konjugált (direkt) bilirubin - Dr. Balaicza Erika. A bilirubin egy festékanyag, mely az epében található. Egyrészt a vörösvértestek természetes elpusztulása során szabadul fel, másrészt a májban, csontvelőben termelődik. Az összes bilirubin nem-konjugált, valamint konjugált (glükuronsavval kapcsolódott) formából tevődik össze. Egészséges emberekben a bilirubin döntő .. Bilirubin | Házipatika. A vörös vértestekben lévő hemoglobin első lebontási terméke a konjugálatlan bilirubin (indirekt bilirubin), mely a májban konjugált bilirubinná (direkt bilirubin) alakul át. Míg az első egyáltalán nem ürül a vesén keresztül, addig az utóbbinak kb. 1%-a szűrődik ki a vizelettel, a többi a májon keresztül az epével .. Mire utalhat a magas bilirubin szint? - Orvos válaszol - WEBBeteg. Totál bilirubin 52, 7 umol/l (normál értékek 5, 0-21, 0) Direkt bilirubin 5, 6 umol/l (normál <5, 0) Egyéb magas értékek a vérvizsgálat során: Vörösvérsejt szám 5, 67 1012/l (normál 3, 50-5, 10) Haemoglobin 178 g/l (normál 115-145) Haematocrit 0, 51% (normál 0, 35-0, 45) Tünetként alkalomszerűen a tenyér bőrének halvány sárga színét, és egy alk.. Mit jelez a magas bilirubinszint? - Életmód | Femina. A direkt bilirubin normálértékének 0,1-0,3 mg/dl - 1,7-5,0 µmol/L között kell lennie. Amennyiben a laboreredmény ennél magasabb szint et mutat, úgy májbetegség - például májgyulladás, májdaganat -, illetve epeút-elzáródás, epekő vagy hasnyálmirigy-betegség állhat a háttérben.. Mit jelez a magas bilirubinszint a laboreredményben? A máj állapotára .. Az összbilirubin normálértéke 20 umol/liter alatt van, míg a direkt bilirubin normális szintje 1-5 umol/l. A problémát a magas bilirubinszint jelenti. A szintje elsősorban a májat és az epeutat érintő betegségek során nő meg, amikor a májenzimek ezt a sárga színt adó epefestéket nem tudják megfelelőképpen kiválasztani.. Direkt bilirubin magas: Okok, tünetek és kezelési lehetőségek. A direkt bilirubin szintjének emelkedése egy figyelemre méltó jelzés, amely különböző egészségügyi problémákat jelezhet. A bilirubin egy olyan vegyület, amely a vörösvértestek lebomlása során keletkezik, és a májban dolgozzák fel. Ebben a cikkben részletesen foglalkozunk a magas direkt bilirubin szintjének okával, a .. Bilirubin | Lab Tests Online-ES. Naponta a felnőtt egészséges szervezetben körülbelül 250-300 mg bilirubin termelődik, melynek a 85%-a károsodott vagy öreg VVT-k elpusztulásából, a maradék része pedig a csontvelőből vagy a májból származik. A nem konjugált bilirubin a májban szállítódik, ahol glükuronsavval kapcsolódva konjugált bilirubinná válik.. Direkt bilirubin magas: Okok és kezelési lehetőségek. A bilirubin egy epepigment, amely a vörösvértestek lebomlása során keletkezik, és a májban dolgozzák fel. Ebben a cikkben megvizsgáljuk, hogy mi okozhatja a direkt bilirubin magas szintjét, milyen tünetekkel járhat, és milyen kezelési lehetőségek állnak rendelkezésre.. Indirekt bilirubin | Házipatika. A vörös vértestekben lévő hemoglobin, mely a vér vörös színét adja, felszabadul a lebomló vörös vértestekből és átalakul bilirubinná - ez az indirekt bilirubin. A máj enzimrendszere vízoldékonnyá teszi az indirekt bilirubint - ezt nevezik direkt bilirubinnak -, majd az epével kiválasztja a bélbe.. Bilirubin Test: High vs. Low Levels, Direct vs. Indirect - WebMD. A bilirubin test measures the amount of bilirubin in your blood. Its used to help find the cause of health conditions like jaundice, anemia, and liver disease. Bilirubin is an orange-yellow .. Direct Bilirubin - Health Encyclopedia - University of Rochester .. A small amount of bilirubin in your blood is normal. Healthy adults make 250 to 350 milligrams (mg) of bilirubin each day. Some bilirubin is bound to a certain protein (albumin) in the blood. This type of bilirubin is called unconjugated, or indirect, bilirubin. In the liver, bilirubin is changed into a form that your body can get rid of.. Direct & Indirect Bilirubin Test: Normal Levels & Jaundice. Direct & Indirect Bilirubin. Bilirubin passes through two phases. In the first phase, bilirubin binds to albumin, which allows it to be carried from the blood and into the liver. Bilirubin in this phase is called "indirect" or "unconjugated" bilirubin .. Direktes Bilirubin - DocCheck Flexikon. Definition. Das direkte Bilirubin ist die wasserlösliche Form des Bilirubins. Durch das Enzym UDP-Glucuronosyltransferase wird in der Leber Glucuronsäure an Bilirubin konjugiert, es entsteht konjugiertes Bilirubin. Zum direkten Bilirubin wird auch das wasserlösliche Delta-Bilirubin gezählt, bei dem konjugiertes Bilirubin durch eine .. BilR is a gut microbial enzyme that reduces bilirubin to . - Nature. The identification of bilirubin reductase allowed us to profile its abundance in 7,960 metagenomes, showing that bilirubin reduction is a core feature of a healthy adult human microbiome and that .. Bilirubin össz - Medicover. A magas bilirubin szint számos máj- és epeútbetegségre utalhat, mint például hepatitisz vagy cirrózis, illetve alkoholizmust, akár vírusos megbetegedést is jelezhet. Ezek mellett még alultápláltság esetén emelkedhet minimálisan a szintje. Az eredmény azonban önmagában nem számít diagnózisnak, más értékekkel együtt .. Bilirubin - Összes - Laboreredmények - WEBBeteg. A bilirubin a vörösvértestek hemoglobinjának lebontása során keletkezik (a vérben ez az ún. nem-konjugált, indirekt bilirubin). A bilirubin a vérplazmában fehérjékhez kötődve a májba szállítódik, a májsejtek glükuronsavval kapcsolják össze (konjugálják - konjugált, direkt bilirubin). Ezt a konjugált bilirubint a máj .. Bilirubin Test - Testing.com. Bilirubin blood test results may indicate the total level in your blood. Some results may also list conjugated (direct) or unconjugated (indirect) bilirubin levels. These two levels typically add up to the total bilirubin level. Your test results will also include reference ranges, the normal range of bilirubin levels.. Bilirubin nedir? Bilirubin düşüklüğü, yüksekliği, normal değeri. Direkt bilirubin yüksekliği temel olarak safra kanallarındaki tıkanıklık sebebiyle oluşur
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. Direkt ve indirekt bilirubinin toplamına total bilirubin denir.. High Bilirubin Levels: Symptoms, Causes, Tests, and Treatments. High bilirubin levels in adults can result from liver disease, pancreatitis, some cancers, and other health problems. Elevated bilirubin can lead to jaundice, which causes yellowing of the skin .. Liver Function Tests - StatPearls - NCBI Bookshelf. The liver has a significant role in metabolism, digestion, detoxification, and elimination of substances from the body. The liver function tests typically include alanine transaminase (ALT) and aspartate transaminase (AST), alkaline phosphatase (ALP), gamma-glutamyl transferase (GGT), serum bilirubin, prothrombin time (PT), the international .. Jaundice in the Adult Patient | AAFP. Pathophysiology. The classic definition of jaundice is a serum bilirubin level greater than 2.5 to 3 mg per dL (42.8 to 51.3 μper L) in conjunction with a clinical picture of yellow skin and .. Jaundice - StatPearls - NCBI Bookshelf. Jaundice, also known as hyperbilirubinemia,[1] is a yellow discoloration of the body tissue resulting from the accumulation of an excess of bilirubin. Deposition of bilirubin happens only when there is an excess of bilirubin, a sign of increased production or impaired excretion. The normal serum levels of bilirubin are less than 1mg/dl; however, the clinical presentation of jaundice as scleral .. Bilirubin - Wikipedia. Bilirubin (BR) (from the Latin for "red bile") is a red-orange compound that occurs in the normal catabolic pathway that breaks down heme in vertebrates.This catabolism is a necessary process in the bodys clearance of waste products that arise from the destruction of aged or abnormal red blood cells. In the first step of bilirubin synthesis, the heme molecule is stripped from the hemoglobin .. Bilirubin Yüksekliğini Düşürmenin 8 Sağlıklı Yolu. Kan tahlili verdiğinizde bazen total bilirubin yüksekliği tespit edilmektedir. Bu yüksek değerler karaciğer fonksiyonlarının bozulduğunu ifade eder
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. Uzmanlar tarafından ideal kabul edilen bilirubin değerleri Konjuge (direkt) bilirubin seviyesi: 0 ile 0.3 mg/dL arasındadır. Total bilirubin seviyesi: 0.3 ile 1.9 mg/dL arasında .. قراءة تحليل Bilirubin المباشر في الدم وتفسير نتائجه | الطبي. تعد قراءة تحليل Bilirubin المباشر في الدم طبيعية إذا كانت قراءة التحليل تتراوح بين (0 - 0.2) ملغ / ديسيلتر، ويجدر الإشارة أن قراءة التحليل قد تختلف من مختبر إلى آخر، كما أنها تختلف باختلاف العمر والجنس والحالة الصحية للفرد.. Bilirubinuria - StatPearls - NCBI Bookshelf. Bilirubinuria is the presence of bilirubin in the urine. It can be detected by the standardized urine dipstick, mostly referred to as urinalysis in most hospitals worldwide. Bilirubin and related breakdown metabolites are well known for causing the characteristic coloring in bile and stool; however, its presence in the urine is not normal, and for it to be present there, it must be water .. Bilirubin Levels Chart (Normal, Low, High Bilirubin Levels Explained). Indirect bilirubin 0.8, 0.7, 0.6, 0.5,0.4, and 0.3 are all normal levels of blood bilirubin. Total bilirubin level 0.9,0.8,0.7,0.6,0.5,0, and 4.0 are normal and not jaundice whatever is the result of direct and indirect bilirubin
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. Recommendation: if its the first time you take a bilirubin test, there is no further investigation when results .. Infant jaundice - Symptoms & causes - Mayo Clinic. Infant jaundice is yellow discoloration of a newborn babys skin and eyes. Infant jaundice occurs because the babys blood contains an excess of bilirubin (bil-ih-ROO-bin), a yellow pigment of red blood cells. Infant jaundice is a common condition, particularly in babies born before 38 weeks gestation (preterm babies) and some breast-fed babies.
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. Low Bilirubin Levels: Symptoms, Causes, and Potential Risks - Healthline. Conjugated (direct) bilirubin. This type is created when bilirubin attaches to (conjugates with) glucuronic acid in the liver before being excreted. This type of bilirubin is what makes your urine .. 胆红素检测 - 妙佑医疗国际 - Mayo Clinic. 目的. 胆红素检测通常包含在肝脏健康检查组合项目中。. 胆红素检测可用于：. 检查黄疸，即由胆红素水平升高引起的皮肤和眼睛发黄。. 这种检测通常用于测量新生儿的胆红素水平，可确定有无婴儿黄疸病症。. 确定肝脏处和胆囊处的胆管是否堵塞。. 帮助检测 .. Bilirubin direktni u krvi ili mokraći • LekarInfo 2021. Bilirubin direktni 2. Ovaj test traži bilirubin u vašoj krvi ili urinu. Bilirubin je supstanca napravljena kada vaše telo razgrađuje stara crvena krvna zrnca. To je normalan proces. Bilirubin je takođe deo žuči koju vaša jetra pravi da bi pomogla probavi hrane koju jedete. Mala količina bilirubina u krvi je normalna.. Direct Bilirubin | San Diego Hospital, Healthcare - Health Library
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. A small amount of bilirubin in your blood is normal. Healthy adults make 250 to 350 milligrams (mg) of bilirubin each day
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. Some bilirubin is bound to a certain protein (albumin) in the blood. This type of bilirubin is called unconjugated, or indirect, bilirubin. In the liver, bilirubin is changed into a form that your body can get rid of.. Bilirubin Nedir? Değer Aralığı Nedir? Yüksekliği Düşüklüğü Neyi İfade .. İnsan vücudunda bulunması gereken normal bilirubin seviyesi direk ve total bilirubin olmak üzere iki farklı aralıkta değerlendirilir. Direkt bilirubin için 0 ve 0,3 mg aralığı, total bilirubin için ise 0,3 ve 1,9 mg aralığında ideal ve sağlıklı olan değer aralıklarıdır. Bilirubin yüksekliği ve düşüklüğü oldukça .. Diet for Jaundice: Foods to Eat and Foods to Avoid - Healthline. Quick tips. Stay hydrated. Water, coffee, or tea can support hydration and liver function. Eat a variety of fruits and vegetables every day
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. Look for high fiber foods, such as oatmeal, broccoli .. Gilbert syndrome - Symptoms & causes - Mayo Clinic. Symptoms. The most frequent sign of Gilbert syndrome is an occasional yellowish tinge of the skin and the whites of the eyes as a result of slightly higher levels of bilirubin in the blood. In people with Gilbert syndrome, bilirubin levels may increase due to: Illness, such as a cold or the flu. Fasting or eating a very low-calorie diet.. Bilirubin blood test: MedlinePlus Medical Encyclopedia. It is normal to have some bilirubin in the blood. A normal level is: Direct (also called conjugated) bilirubin: less than 0.3 mg/dL (less than 5.1 µmol/L) Total bilirubin: 0.1 to 1.2 mg/dL (1.71 to 20.5 µmol/L) Normal value ranges may vary slightly among different laboratories. Some labs use different measurements or may test different samples.. Unconjugated Hyperbilirubinemia - StatPearls - NCBI Bookshelf. Hyperbilirubinemia is a condition defined as elevated serum or plasma bilirubin levels above the reference range of the laboratory, and it is due to disorders of bilirubin metabolism. Depending on the form of bilirubin present in serum, hyperbilirubinemia can be further classified as unconjugated (indirect) or conjugated (direct). Unconjugated hyperbilirubinemia (albumin-bound) usually results .. Gilberts Syndrome: Symptoms, Causes, Tests & Treatment - Cleveland Clinic. Gilberts syndrome is an inherited (genetic) liver disorder that affects the bodys ability to process bilirubin. Bilirubin is yellow liquid waste that occurs naturally as the body breaks down old red blood cells. People with Gilberts syndrome dont produce enough liver enzymes to keep bilirubin at a normal level.
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. Össz-bilirubin | Házipatika. A bilirubin a vérfesték lebontási terméke, szintje a vörös vértestek fokozott lebomlása, májbetegségek és epeelfolyási akadály esetén emelkedhet. ez az indirekt bilirubin. A máj enzimrendszere vízoldékonnyá teszi (ez a direkt bilirubin), majd az epével kiválasztja. A bélben lévő epefesték egy része visszaszívódik .. Bilirubin | eClinpath. In this species, direct bilirubin concentrations are increased in cholestasis but are typically lower than the increases in indirect bilirubin concentrations (the direct bilirubin proportion is usually <50% of total bilirubin and often <25-30% of the total bilirubin concentration) (Traub et al 1982, McGorum et al 1999, Peek and Divers 2000 .. Physiology, Bilirubin - StatPearls - NCBI Bookshelf. Bilirubin is an important metabolite of heme (ferroprotoporphyrin IX), a coordination complex that serves to coordinate iron in various proteins. It is a potentially toxic substance. However, the body has developed mechanisms for its safe detoxification and disposition. Bilirubin and its metabolites also provide the distinctive yellow color to bile and stool and a lesser degree, urine. This .. #293 The Best of Liver Tests with Dr. Elliot Tapper. Bilirubin elevations. First, fractionate the total bilirubin. If >50% is direct= direct hyperbilirubinemia. Otherwise=indirect bilirubinemia. Usually with indirect hyperbilirubinemia 80-90% of bilirubin will be indirect. For indirect hyperbilirubinemia, check LDH, haptoglobin and reticulocyte count to evaluate for hemolysis.. Low Bilirubin: Meaning, Test Results, Average Range - Verywell Health. Total bilirubin represents a combination of all the bilirubin in your bloodstream. It is a combination of indirect and direct bilirubin levels. An average adult value for total bilirubin normal range is 0.3 to 1.0 mg/dL. Understanding Common Blood Tests and What They Mean.. اختبار البيليروبين - Mayo Clinic (مايو كلينك). لماذا يتم إجراء ذلك. عادةً ما يكون اختبار البيليروبين واحدًا من مجموعة اختبارات تُجرى للتحقق من صحة الكبد. يمكن إجراء اختبار البيليروبين من أجل: التحقق من الإصابة باليرقان، وهو مرض يؤدي إلى .. Uses, Side Effects, and Procedure of a Bilirubin Test - Verywell Health. Uses, Side Effects, and Procedure of a Bilirubin Test. Bilirubin tests, which measure the levels of total bilirubin, unconjugated (indirect) and conjugated (direct) bilirubin in your blood, are a group of blood tests that are used to help evaluate a variety of gastrointestinal and blood diseases. Bilirubin is a chemical component inside red .. Bilirubin: Reference Range, Interpretation, Collection and Panels. Direct bilirubin correlates with conjugated bilirubin but tends to overestimate actual conjugated bilirubin, as it includes both the conjugated bilirubin and bilirubin covalently bound to albumin (delta-bilirubin). Indirect bilirubin correlates with unconjugated bilirubin but tends to underestimate unconjugated bilirubin, as a portion of the .. High Bilirubin Levels (Hyperbilirubinemia): Symptoms, Causes. The indirect (unconjugated) bilirubin levels can be inferred from the total and direct bilirubin values. Although labs may use different reference ranges, there are generally accepted normal levels. Bilirubin is often included as part of a panel of tests that evaluate liver function and enzymes, including:. Monitoring Neonatal Bilirubin after Discharge | Pediatrics In Review .. Neonatal jaundice affects more than 80% of newborns and is the most common cause of readmission after discharge from the nursery. From the day of discharge to day 5 after birth is critical because the bilirubin level peaks during this period for most neonates. In 2022, the American Academy of Pediatrics (AAP) updated its 2004 clinical practice guideline and 2009 commentary that included .. Gilberts Syndrome: Symptoms, Causes, Diagnosis, and Treatment
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. exercising vigorously. not eating for a long period of time. not drinking enough water. not sleeping enough. being sick or having an infection. recovering from surgery. menstruating. cold exposure .. Bilirubin - Tanda, Penyebab, Gejala, Cara Mengobati
. Tes bilirubin darah akan mendapatkan perhitungan akurat dari ketiga jenis bilirubin dalam darah: direct, indirect, dan total. Indikasi Pemeriksaan bilirubin. Pemeriksaan bilirubin paling sering digunakan untuk memeriksa adanya kerusakan hati. Karena organ inilah yang memperoses dan mengeluarkan bilirubin dari tubuh melalui feses dan sebagian .. Bilirubin, Direct | Test Detail | Quest Diagnostics. Bilirubin, Direct - Measurement of the levels of bilirubin is used in the diagnosis and treatment of liver, hemolytic, hematologic, and metabolic disorders, including hepatitis and gall bladder obstruction. The assessment of direct bilirubin is helpful in the differentiation of hepatic disorders. The increase in total bilirubin associated with obstructive jaundice is primarily due to the .. BILID - Overview: Bilirubin Direct, Serum - Mayo Clinic Laboratories. Direct bilirubin is a measurement of conjugated bilirubin. Jaundice can occur as a result of problems at each step in the metabolic pathway. Disorders may be classified as those due to: increased bilirubin production (eg, hemolysis and ineffective erythropoiesis), decreased bilirubin excretion (eg, obstruction and hepatitis), and abnormal .. Chỉ số Bilirubin nói gì về sức khỏe của bạn? | Vinmec. Bác sĩ đã có hơn 10 năm học tập, nghiên cứu và làm việc trong lĩnh vực nội tiết. Bilirubin là sắc tố mật chính hình thành từ sự thoái giáng của heme trong tế bào hồng cầu. Xét nghiệm Bilirubin trong máu là xét nghiệm đặc biệt cần thiết để đánh giá tình trạng sức .. Bilirubin blood test Information | Mount Sinai - New York. It is normal to have some bilirubin in the blood. A normal level is: Direct (also called conjugated) bilirubin: less than 0.3 mg/dL (less than 5.1 µmol/L) Total bilirubin: 0.1 to 1.2 mg/dL (1.71 to 20.5 µmol/L) Normal value ranges may vary slightly among different laboratories. Some labs use different measurements or may test different samples.. Bilirubin Blood Test: Procedure, Preparation, and Risks - Healthline. In an older child or adult, normal values of direct bilirubin are from 0-0.4 milligrams per deciliter (mg/dL). Normal values of total bilirubin are from 0.3-1.0 mg/dL.. Bilirubin - an overview | ScienceDirect Topics. Indirect (unconjugated) bilirubin, which does not dissolve in water, and thus cannot be measured. As such, it is derived from both the total and direct bilirubin measurements. It travels through the blood to the liver, where it is changed into a soluble form. 2. Direct (or conjugated) bilirubin, which is the conjugated form of bilirubin.. Bilirubin Test: Normal & High Levels in Adults & Newborns - MedicineNet. Normal values of direct bilirubin range from 0 to 0.4 mg/dL. Total bilirubin (direct and indirect) ranges from about 0.2 to 1.2 mg/dL (some lab values range as high as 1.9 mg/dL). Medical literature sources have minor variations in "normal" levels). Low levels of bilirubin may be due to certain medications such as theophylline (Elixophyllin .. High Bilirubin Levels: Meaning of Elevated Bilirubin - Healthgrades. Summary. Elevated bilirubin or hyperbilirubinemia is when the levels of bilirubin in the blood are higher than usual. Bilirubin is a metabolic waste product present in the blood. It forms when red blood cells break down. High levels of bilirubin can cause dark urine, pale stool, and jaundice, which is yellowing of the skin and whites of the eyes.. Bilirubin, Direct | Test Detail | Quest Diagnostics. Bilirubin, Direct - Measurement of the levels of bilirubin is used in the diagnosis and treatment of liver, hemolytic, hematologic, and metabolic disorders, including hepatitis and gall bladder obstruction. The assessment of direct bilirubin is helpful in the differentiation of hepatic disorders. The increase in total bilirubin associated with obstructive jaundice is primarily due to the .. Causes of High / Low Bilirubin Levels + Health Benefits. Therefore, increased direct bilirubin is usually a sign of liver diseases, such as viral or autoimmune hepatitis, or alcoholic liver disease [29, 30, 31]. Indirect bilirubin can increase in conditions such as fatty liver or in liver diseases which are associated with increased red blood cell destruction [32, 33]..